Pantothenic Acid
INGREDIENTS: Pantothenic Acid, Also known as Vitamin B5
OTHER NAMES: Acide D-Pantothénique, Acide Pantothénique, Ácido Pantoténico, Alcool Pantothénylique, B Complex Vitamin, Calcii Pantothenas, Calcium D-Pantothenate, Calcium Pantothenate, Complexe de Vitamines B, D-Calcium Pantothenate, D-Panthenol, D-Panthénol, D-Pantothénate de Calcium, D-Pantothenyl Alcohol, Dexpanthenol, Dexpanthénol, Dexpanthenolum, Pantéthine, Panthenol, Panthénol, Pantothenate, Pantothénate, Pantothénate de Calcium, Pantothenol, Pantothenylol, Vitamin B-5, Vitamin B5, Vitamina B5, Vitamine B5
- Overview
- Usage
- Safety
- Interactions
- Dosing
- Others
| Usage | Effectiveness |
|---|---|
|
|
| Proven | Safety |
USAGE AND EFFECTIVENESS
| Usage | Effectiveness |
|---|---|
| Vitamin B5 Deficiency |
Effective (Increase pantothenic acid levels) Shown in one strong clinical study to prevent and treat pantothenic acid deficiency One strong clinical study to support the point above |
| Constipation |
Mild effectiveness (Improve bowel movement) One clinical study showing decrease in the time to a bowel movement when pantothenic acid is used for 5 days; but clinical study is not robust enough; more evidence is needed to support the above |
| Acne |
Unclear effectiveness 2 clinical studies showed limited reduction of symptoms for individuals with mild to moderate acne when skin preparation with vitamin B5 was used; results were also inconclusive due to poor study design (no comparator group); More evidence needed |
| Eczema |
Unclear effectiveness 1 clinical study showed skin preparation with vitamin B5 was as effective as another moisturiser in terms of effect in reducing symptoms and relapses; results were inconclusive due to poor study design (unknown comparator group) and uncertainty of whether beneficial effects were caused by Vitamin B5 or other components of the cream; More evidence needed |
| Eye Injury |
Unclear effectiveness (Reduce eye pain) Two clinical studies showing conflicting results (One shows that pantothenic acid helps to reduce eye pain and discomfort while another shows no improvement in wound healing); more evidence is needed |
| Postoperative Recovery |
Unknown effectiveness (supposed to improve intestine movement) One study showed that it did not reduce post surgery paralysis of intestine; More evidence needed |
| Radiation Dermatitis |
Unclear effectiveness 2 studies showed that usage of cream or ointment containing Patothenic Acid, did not show benefits; More evidence needed Radiation Dermatitis is a complication of cancer radiotherapy, causing symptoms such as redness, itch, pain, broken skin, and being susceptible to infection. |
| Rhinosinusitis |
Unclear effectiveness (Improve symptoms of rhinosinustis) One clinical study to support the above point (reduces nasal discharge but not other symptoms of rhinosinustis as compared to saline nasal spray); but clinical study is not robust enough; more evidence needed |
| Skin Irritation |
Unclear effectiveness (Reduce skin irritation) Two clinical studies showing conflicting results (One shows reduction in skin water loss, roughness, and inflammation while another shows ineffectiveness of pantothenic acid in preventing skin irritation); more evidence is needed |
| Sore Throat |
Unclear effectiveness (Improve symptoms of postoperative sore throat) One clinical study to support the above point (reduces incidence and severity of postoperative sore throat); but clinical study is not robust enough; more evidence needed |
| Alcohol Addiction |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
| Allergic Rhinitis |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
| Anxiety |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
| Asthma |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
| Attention Deficit Hyperactivity Disorder (ADHD) |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
| Osteoarthritis |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
| Rheumatoid Arthritis |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
| Sports Performance |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
General Safety
- Generally safe when used appropriately; Generally unsafe when used in large amount
Pregnant/ Breastfeeding
- Generally safe when used during pregnancy and breastfeeding; Unknown safety when adequate intake is exceeded, avoid using in large amount
Children
- Generally safe when applied appropriately and as a skin preparation
Elderly
- Little data to show it is safe or otherwise; avoid if possible
Special to Note
- Unknown
Contraindications
- Generally not known to affect individuals with concurrent diseases; past reports of rare issues with worsening of bowel obstruction, bleeding conditions and inflammatory bowel disease
Side Effects
-
Generally safe; side effects may include:
Heart:May increase fluid accumulation around the heart
Skin:May cause itching, burning, skin irritation, rashes, and eczema when using externally
Digestive system:May cause diarrhoea
- Medicines
None known; However, antibiotics may reduce the pantothenic acid level in the body (though not to the extent that may affect health) - Supplements
None known - Food
None known - Lab Tests
None known
- General (Adults)
18 years and older: 5mg daily; Pregnant: 6mg daily; Lactating: 7mg daily - Constipation (Adults)
400mg daily for up to 5 days - Vitamin B Deficiency (Adults)
Consume 5-10mg daily - Postoperative Sore Throat (Adults)
Consume 200mg lozenges, 30 minutes before anesthesia - Eye Injury (Adults)
Apply 5% eyedrops twice daily for up to 30 days - Skin Irritation (Adults)
Apply 1-5% twice daily for up to 30 days - Oral (Children)(Daily intake)
0-6 months, 1.7mg; 7-12 months, 1.8mg; 1-3 years, 2mg; 4-8 years, 3mg; 9-13 years, 4mg; 14-17 years, 5mg
- General Information
- Pantothenic acid is used by consumers for Vitamin B deficiency, acne, allergy reactions, ADHD, heart failure, and others
- How does it work?
- Contains chemicals that have laxatative effects, anti-inflammatory and stimulate skin repair; Pantothenic Acid plays an important role in supporting metabolism - deficiency causes sleepiness, tiredness, headache, feeling of pins and needles in extremities, muscle weakness, behaviour change and being prone to infection.
| Effectiveness Score | What does it mean | Action to be taken by you |
|---|---|---|
| 5 | Gold Standard | You should always consider taking this supplement. Do check if your health professional has any objection to you taking this supplement. |
| 4 | Effective | This supplement may be helpful. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 3 | Mildly Effective | This supplement may be mildly helpful. You may consider taking this if the benefit outweighs the risk. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 2 | Unclear Effectiveness due to Conflicting Results or Limited Benefit | This supplement may not provide a clear benefit to the issue(s) you seek to resolve. Do consult your health professional if you still decide to go ahead to take this. |
| Effectiveness Score | What does it mean | Action to be taken by you |
|---|---|---|
| 5 | Gold Standard | You should always consider taking this supplement. Do check if your health professional has any objection to you taking this supplement. |
| 4 | Effective | This supplement may be helpful. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 3 | Mildly Effective | This supplement may be mildly helpful. You may consider taking this if the benefit outweighs the risk. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 2 | Unclear Effectiveness due to Conflicting Results or Limited Benefit | This supplement may not provide a clear benefit to the issue(s) you seek to resolve. Do consult your health professional if you still decide to go ahead to take this. |
| 1 | Unknown Effectiveness | There is no evidence of benefit for taking this supplement. Do consult your health professional if you still decide to go ahead to take this. |
| 0 | Proven to be Not Effective | Taking this supplement has been proven to be ineffective. Do consult your health professional if you still decide to go ahead to take this. |
| Amount of Medical Evidence | What does it mean | Action to be taken by you |
|---|---|---|
| 5 | Proven by One or More Well Designed Analysis of Several Well Designed Medical Studies | You can rest assured that this supplement can do what it claims to do. |
| 4 | Proven by several well designed medical studies | You have good confidence that this supplement will do what it claims to do. |
| 3 | Proven by One Well Designed Medical Study | You have some confidence that this supplement will do what it claims to do. |
| 2 | Proven by One or Several Not Well Designed Medical Studies | There may be doubts about whether this supplement can do what it claims. Consider if this is necessary. |
| 1 | No Study Done or Proven by Weakly Designed Medical Studies | There are many doubts about whether this supplement can do what it claims. Consider if this is necessary. |
| 0 | Proven to be Ineffective or Harmful | You should strongly consider not to use this unless advised by your health professionals. |
| Safety Score | What does it mean | Action to be taken by you |
|---|---|---|
| 5 | Safe for Everyone | This supplement is most likely to be safe for you. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 4 | Safe for General Population, with Unknown Effect on Special Population | This supplement is likely to be safe for you, except for certain circumstances. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 3 | ||
| 2 | Safe for General Population but may be Unsafe for Certain Population or have Certain Rare Side Effect | This supplement may be safe for you if you do not have any medical conditions or concurrent medication. Do consult your health professional before taking it. |
| 1 | Unknown Safety | Unless you are very healthy and have no concurrent medical conditions and medication, you should not take it. Even if safety is not an issue, you should only consider taking it if the benefit is deemed to be more than the risk. Please consult your health professional should you decide to take the supplement. |
| 0 | Unsafe | You must not take this. Please consult your health professional should you decide otherwise. |
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