Dong Quai
INGREDIENTS: Ferulic acid, ligustilide, angelicide, brefeldin A, butylphthalide, nicotinic acid, succinic acid, angelica polysaccharide, and phytosterols such as beta-sitosterol, uracil, adenine, carvacrol, safrole, isosafrole, sesquiterpenes, n-dodecanol, n-tetradecanol, palmitic acid, angelic acid, myristic acid, psoralens, vitamin A, carotenoids, vitamin E, vitamin C, vitamin B12, biotin, folic acid, calcium, magnesium, zinc and potassium, 0.4% to 0.7% volatile oil, angelol, angelicone, osthol, psoralen, oxypeucedanin and bergapten
OTHER NAMES: Angelica China, Angelica sinensis, Angelica polymorpha var. sinensis, Angelicae Gigantis Radix, Angelique Chinoise*, Angelique de Chine*, Chinese Angelica, Dang Gui, Danggui, Danguia, Dang Gui Shen, Dang Gui Tou, Dang Gui Wei, Don Quai, Kinesisk Kvan, Ligustilides, Radix Angelicae Gigantis, Radix Angelicae Sinensis, Tang Kuei, Tan Kue Bai Zhi, Tanggwi, Toki (*modified from non-English name with special characters/symbols)
- Overview
- Usage
- Safety
- Interactions
- Dosing
- Others
Usage | Effectiveness |
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Proven | Safety |
USAGE AND EFFECTIVENESS
Usage | Effectiveness |
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Heart & Blood Vessel Diseases |
Mild effectiveness (Reduces and improve symptoms of coronary heart diseases) One clinical study showing reduction in frequency, severity of chest pain, increase in exercise tolerance, and improvement in left ventricular function; but clinical study is not robust enough; more evidence is needed to support the above |
Lung Inflammation |
Mild effectiveness (Improves symptoms of pneumonia) One clinical study showing improvement in lung function index, six-minute walking distance, in individuals with idiopathic interstitial pneumonia; but clinical study is not robust enough; more evidence is needed to support the above |
Menopausal Symptomse Symptoms |
Mild effectiveness (Improves Menopausal Symptomse symptoms) Several clinical studies showing improvement in Menopausal Symptomse symptoms such as hot flushes, night sweats and sleep quality but unclear if effects were due to dong quai or other ingredients ; but clinical study is not robust enough; more evidence is needed to support the above |
Migraine Headache |
Mild effectiveness (Reduces frequency of menstrual-associated migraine attacks) One clinical study showing reduction in frequenct of menstrual associated migraine attacks; but clinical study is not robust enough; more evidence is needed to support the above |
Premature Ejaculation |
Mild effectiveness (Improves time to ejaculation) One clinical study showing improvement in time take to ejaculation; but clinical study is not robust enough; more evidence is needed to support the above |
High Blood Pressure in Lungs |
Mild effectiveness (Reduces lung aterial pressure) One clinical study showing reduction in lung aterial pressure and lung vascular resistance; but clinical study is not robust enough; more evidence is needed to support the above |
Stroke |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
Skin Conditions |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
Allergies |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
High Blood Pressure |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
Infertility |
Unknown effectiveness No clinical study to support the above point; More evidence needed |
Multiple Conditions |
To read more, please visit https://vitzest.com/dong_quai |
General Safety
- Generally safe when used orally and appropriately; Generally unsafe when used in large amounts for a long term
Pregnant/Breastfeeding
- Generally unsafe for due to uterine stimulant and relaxant effects and possible increase in blood pressure in breastfed infants; do avoid
Children
- Little data to show it is safe or otherwise; avoid if possible
Elderly
- Little data to show it is safe or otherwise; avoid if possible
Special to Note
- Individuals are advised to not take the supplement 2 weeks before the operation.
Contraindications
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May increase risk of bleeding in individuals with bleeding disorders
May worsen breast cancer in women
May worsen hormone sensitive cancers/conditions
May increase risk of blood clotting in individuals with protein S deficiency
May interfere with bleeding during surgery
Side Effects
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Generally safe; side effects may include
Heart:May cause increase in blood pressure
Skin:May cause photosensitivity an photodermatitis
Hormones:May cause swelling of breast tissue in men
Digestive System:May cause burping and gas
Brain/CNS:May cause headache
Ear/Eye:One case of temporary vision loss was reported
Lungs:One case of allergic asthma and rhinitis was reported due to occuaptional exposure
- Medicines
Medium to High severity interactions with medicines for blood clotting and estrogens - Supplements
Medium to High severity interactions with herbs and supplements with blood clotting effects (e.g dang gui (angelica), clove, danshen, garlic, ginger, ginkgo, panax ginseng, poplar, red clover, willow and others), and black pepper - Food
None known - Lab Tests
None known
- Menopausal Symptoms (Adults)
Consume five chewable tablets of specific combination product containing dong quai and chamomile daily for 12 weeks; Consume combination formula containing American ginseng, black cohosh, dong quai, milk thistle, red clover and vitex agnus-castus twice daily for 3 months; Consume 500mg herbal combination product containing burdock root, licorice root, motherwort, dong quai, and Mexican wild yam root three times daily for 3 months - Migraine Headache (Adults)
Consume combination of 60mg soy isoflavones, 100mg dong quai, and 50mg black cohosh daily for 24 weeks - High Blood Pressure in Lungs (Adults)
Administer 250mL of solution containing 25% dong quai once daily for 5-10 days intravenously in patients with COPD and high blood pressure in lungs - Coronary Heart Disease (Adults)
Administer 20mL solution containing dong quai, ginseng, and astragalus intravenously daily for 2 weeks - Premature Ejaculation (Adults)
Apply multi-ingredient cream prepared to contain Panax ginseng root, dong quai, Cistanches deserticola, Zanthoxyl species, Torlidis seed, clove flower, Asiasari root, cinnamon bark and toad venom to the gland penis 1 hour before intercourse, and washed off immediately before intercourse
- General Information
- While there is a lack of clinical studies, Dong Quai is used by consumers for lung inflammation, migraine headache, skin conditions, allergies, osteoporosis, stomach ulcer, rheumatoid arthritis, vitiligo
- How does it work?
- Contains chemicals that regulate heart rate, reduces blood coagulation, blood pressure, inflammation, platelets effects, ulcer, neoplastic properties, affects skin, genitourinary, blood, liver, immune system, lungs, and uterine effects and also helps with hormonal system
Effectiveness Score | What does it mean | Action to be taken by you |
---|---|---|
5 | Gold Standard | You should always consider taking this supplement. Do check if your health professional has any objection to you taking this supplement. |
4 | Effective | This supplement may be helpful. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
3 | Mildly Effective | This supplement may be mildly helpful. You may consider taking this if the benefit outweighs the risk. Do consult your health professional if you have any medical condition or if you are taking any medication. |
2 | Unclear Effectiveness due to Conflicting Results or Limited Benefit | This supplement may not provide a clear benefit to the issue(s) you seek to resolve. Do consult your health professional if you still decide to go ahead to take this. |
Effectiveness Score | What does it mean | Action to be taken by you |
---|---|---|
5 | Gold Standard | You should always consider taking this supplement. Do check if your health professional has any objection to you taking this supplement. |
4 | Effective | This supplement may be helpful. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
3 | Mildly Effective | This supplement may be mildly helpful. You may consider taking this if the benefit outweighs the risk. Do consult your health professional if you have any medical condition or if you are taking any medication. |
2 | Unclear Effectiveness due to Conflicting Results or Limited Benefit | This supplement may not provide a clear benefit to the issue(s) you seek to resolve. Do consult your health professional if you still decide to go ahead to take this. |
1 | Unknown Effectiveness | There is no evidence of benefit for taking this supplement. Do consult your health professional if you still decide to go ahead to take this. |
0 | Proven to be Not Effective | Taking this supplement has been proven to be ineffective. Do consult your health professional if you still decide to go ahead to take this. |
Amount of Medical Evidence | What does it mean | Action to be taken by you |
---|---|---|
5 | Proven by One or More Well Designed Analysis of Several Well Designed Medical Studies | You can rest assured that this supplement can do what it claims to do. |
4 | Proven by several well designed medical studies | You have good confidence that this supplement will do what it claims to do. |
3 | Proven by One Well Designed Medical Study | You have some confidence that this supplement will do what it claims to do. |
2 | Proven by One or Several Not Well Designed Medical Studies | There may be doubts about whether this supplement can do what it claims. Consider if this is necessary. |
1 | No Study Done or Proven by Weakly Designed Medical Studies | There are many doubts about whether this supplement can do what it claims. Consider if this is necessary. |
0 | Proven to be Ineffective or Harmful | You should strongly consider not to use this unless advised by your health professionals. |
Safety Score | What does it mean | Action to be taken by you |
---|---|---|
5 | Safe for Everyone | This supplement is most likely to be safe for you. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
4 | Safe for General Population, with Unknown Effect on Special Population | This supplement is likely to be safe for you, except for certain circumstances. Do consult your health professional if you have any medical condition or if you are taking any medication. |
3 | ||
2 | Safe for General Population but may be Unsafe for Certain Population or have Certain Rare Side Effect | This supplement may be safe for you if you do not have any medical conditions or concurrent medication. Do consult your health professional before taking it. |
1 | Unknown Safety | Unless you are very healthy and have no concurrent medical conditions and medication, you should not take it. Even if safety is not an issue, you should only consider taking it if the benefit is deemed to be more than the risk. Please consult your health professional should you decide to take the supplement. |
0 | Unsafe | You must not take this. Please consult your health professional should you decide otherwise. |
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