Papaya
INGREDIENTS: Leaves contain papain and carpain, while seeds have saponins, terpenoids, flavanoids, and alkaloids. Unripe fruit contains papain and ripe fruit contains papain inhibitor and carotenoids.
OTHER NAMES: Banane de Prairie, Caricae Papayae Folium, Chirbhita, Erandachirbhita, Erand Karkati, Green Papaya, Mamaerie, Melon Tree, Melonenbaumblaetter, Papaw, Papaya Fruit, Papayas, Papaye, Papaye Verte, Papayer, Papita, Paw Paw, Pawpaw, Carica papaya L., Betik petik, Chichput, Fan kua, Fermented papaya, Gandul, Gantung, Katela, Kates, Kavunagaci, Kepaya, Kuntaia, Kuo, Lechoso, Lohong si phle, Mamao, Maoaza, Mu kua, Papailler, Papayer, Pepol, Pepol, Tinti, Wanshou
- Overview
- Usage
- Safety
- Interactions
- Dosing
- Others
| Usage | Effectiveness |
|---|---|
|
|
| Proven | Safety |
USAGE AND EFFECTIVENESS
| Usage | Effectiveness |
|---|---|
| Cancer |
Mild effectiveness (Reduce risk of developing cancer) Several clinical studies showing reduction in the probability of developing gallbladder and colorectal cancer; but clinical study is not robust enough; more evidence is needed to support the above |
| Dengue Fever |
Unclear effectiveness (Increase platelet count) Two clinical studies showing increase in platelet count; effects of papaya on other symptoms and mortality of dengue fever are unknown; more evidence is needed |
| Diabetes |
Unclear effectiveness (Reduce blood sugar level) One clinical study to support the above point; but clinical study is not robust enough; More evidence needed |
| Gingivitis |
Unclear effectiveness (Reduce bleeding incidences) One clinical study to support the above point; does not significantly reduce bleeding episodes; More evidence needed Gingivitis is a condition where the gums are inflammed |
| Human Papillomavirus |
Unclear effectiveness (Reduce risk of HPV) One clinical study to support the above point; but clinical study is not robust enough; More evidence needed Human papillomavirus (HPV) is condition where virus is passed through skin contact, causing genital warts and even cancers such as cervical cancers |
| Periodontitis |
Unclear effectiveness (Reduce bleeding episodes, and improve plaque and gingvitis) One clinical study to support the above point; but clinical study is not robust enough; More evidence needed Periodontitis is condition where there is a serious dental infection with symptoms such as swollen and bleeding gum, toothache and pus in the gum; it may lead to possible loss of teeth and other health complications (e.g. heart disease and worsening of blood sugar control). |
| Wounds |
Unclear effectiveness (Shorten repair process of the skin) One clinical study to support the above point; but clinical study is not robust enough; More evidence needed |
General Safety
- Generally safe when used orally and appropriately; Generally unsafe to consume unripe fruit
Pregnant/Breastfeeding
- Generally safe as food in normal amount and when used appropriately; Generally unsafe to consume unripe fruit
Children
- Little data to show it is safe or otherwise; avoid if possible
Elderly
- Little data to show it is safe or otherwise; avoid if possible
Special to Note
- Avoid consumption of unripe fruit; Avoid for 2 weeks before surgery
Contraindications
-
May affect blood sugar levels in individuals with diabetes
May cause low blood sugar in healthy individuals
May worsen hypothyroidism and interfere therapy of individuals with hypothyroidism
May cause allergy reaction in individuals with latex and papain allergy
Avoid for 2 weeks before surgery
Side Effects
-
Generally safe; side effects may include:
Skin:May cause skin allergic reactions which includes rashes and skin swelling
Digestive System:May cause nausea and vomiting; One case of esopheagal perforation
Others:High levels of arsenic in the body
- Medicines
Medium to High severity interactions with medicines for the heart rate irregularity, lowering blood sugar, thyroid replacement and blood thinning - Supplements
Medium to High severity interactions with herbs and supplements that lower blood sugar level (e.g Fenugreek, Panax Ginseng, Siberian Ginseng and others) - Food
None known - Lab Tests
Interactions with lab test for papain, which is present in papaya leaf
- Dengue fever (Adults)
Consume 0.5 grammes to 3.3 grammes daily for 5 days in divided doses - Diabetes (Adults)
Consume 3 grammes once daily for 12 months - Gingivitis (Adults)
Brush teeth with papaya leaf extract toothpaste twice daily for 2 minutes for up to 4 weeks - Periodontitis (Adults)
Apply 7 grammes of fermented papaya gel onto the affected gum for 15 minutes for up to 10 days - Wound (Adults)
Apply 200 grammes of partially ripe papaya fruit to the edges of the affected wound for 48 hours
- General Information
- Papaya is used by consumers for cancer prevention, HPV, diabetes, dengue fever and others
- How does it work?
- Contains chemicals that may reduce bacterial infections, cancer growth, blood sugar level, inflammation, fungal infections, parasite infections, viral infections, heart rate, male fertility, wound healing time, and may increase iron absorption, immune system stimulation, and brain protection; has antioxidant effect
| Effectiveness Score | What does it mean | Action to be taken by you |
|---|---|---|
| 5 | Gold Standard | You should always consider taking this supplement. Do check if your health professional has any objection to you taking this supplement. |
| 4 | Effective | This supplement may be helpful. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 3 | Mildly Effective | This supplement may be mildly helpful. You may consider taking this if the benefit outweighs the risk. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 2 | Unclear Effectiveness due to Conflicting Results or Limited Benefit | This supplement may not provide a clear benefit to the issue(s) you seek to resolve. Do consult your health professional if you still decide to go ahead to take this. |
| Effectiveness Score | What does it mean | Action to be taken by you |
|---|---|---|
| 5 | Gold Standard | You should always consider taking this supplement. Do check if your health professional has any objection to you taking this supplement. |
| 4 | Effective | This supplement may be helpful. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 3 | Mildly Effective | This supplement may be mildly helpful. You may consider taking this if the benefit outweighs the risk. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 2 | Unclear Effectiveness due to Conflicting Results or Limited Benefit | This supplement may not provide a clear benefit to the issue(s) you seek to resolve. Do consult your health professional if you still decide to go ahead to take this. |
| 1 | Unknown Effectiveness | There is no evidence of benefit for taking this supplement. Do consult your health professional if you still decide to go ahead to take this. |
| 0 | Proven to be Not Effective | Taking this supplement has been proven to be ineffective. Do consult your health professional if you still decide to go ahead to take this. |
| Amount of Medical Evidence | What does it mean | Action to be taken by you |
|---|---|---|
| 5 | Proven by One or More Well Designed Analysis of Several Well Designed Medical Studies | You can rest assured that this supplement can do what it claims to do. |
| 4 | Proven by several well designed medical studies | You have good confidence that this supplement will do what it claims to do. |
| 3 | Proven by One Well Designed Medical Study | You have some confidence that this supplement will do what it claims to do. |
| 2 | Proven by One or Several Not Well Designed Medical Studies | There may be doubts about whether this supplement can do what it claims. Consider if this is necessary. |
| 1 | No Study Done or Proven by Weakly Designed Medical Studies | There are many doubts about whether this supplement can do what it claims. Consider if this is necessary. |
| 0 | Proven to be Ineffective or Harmful | You should strongly consider not to use this unless advised by your health professionals. |
| Safety Score | What does it mean | Action to be taken by you |
|---|---|---|
| 5 | Safe for Everyone | This supplement is most likely to be safe for you. You may consider taking this. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 4 | Safe for General Population, with Unknown Effect on Special Population | This supplement is likely to be safe for you, except for certain circumstances. Do consult your health professional if you have any medical condition or if you are taking any medication. |
| 3 | ||
| 2 | Safe for General Population but may be Unsafe for Certain Population or have Certain Rare Side Effect | This supplement may be safe for you if you do not have any medical conditions or concurrent medication. Do consult your health professional before taking it. |
| 1 | Unknown Safety | Unless you are very healthy and have no concurrent medical conditions and medication, you should not take it. Even if safety is not an issue, you should only consider taking it if the benefit is deemed to be more than the risk. Please consult your health professional should you decide to take the supplement. |
| 0 | Unsafe | You must not take this. Please consult your health professional should you decide otherwise. |
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